Evolution, developmental expression and function of odorant receptors in insects
نویسندگان
چکیده
منابع مشابه
Odorant and Pheromone Receptors in Insects
Since the emergence of the first living cells, survival has hinged on the ability to detect and localize chemicals in the environment. Modern animal species ranging from insects to mammals express large odorant receptor repertoires to detect the structurally diverse array of volatile molecules important for survival. Despite the essential nature of chemical detection, there is surprising divers...
متن کاملSelectivity of odorant receptors in insects
Insect olfactory receptors (ORs) detect chemicals, shape neuronal physiology, and regulate behavior. Although ORs have been categorized as "generalists" and "specialists" based on their ligand spectrum, both electrophysiological studies and recent pharmacological investigations show that ORs specifically recognize non-pheromonal compounds, and that our understanding of odorant-selectivity mirro...
متن کاملThe Functional Evolution of Mammalian Odorant Receptors
The Functional Evolution of Mammalian Odorant Receptors by Kaylin Alexis Adipietro University Program in Genetics and Genomics Duke University Date:_______________________ Approved: ___________________________ Hiroaki Matsunami, Supervisor ___________________________ Marc Caron ___________________________ William Dan Tracey ___________________________ Christine Drea ___________________________ ...
متن کاملMonogenic and Monoallelic Expression of Odorant Receptors.
Odorant receptors (ORs) belong to a large gene family of rhodopsin-like G protein-coupled receptors (GPCRs). The mouse OR gene family is composed of ∼1000 OR genes, and the human OR gene family is composed of ∼400 OR genes. The OR genes are spread throughout the genome, and can be found in clusters or as solitary genes in almost all chromosomes. These chemosensory GPCRs are expressed in highly ...
متن کاملFunctional Evolution of Mammalian Odorant Receptors
The mammalian odorant receptor (OR) repertoire is an attractive model to study evolution, because ORs have been subjected to rapid evolution between species, presumably caused by changes of the olfactory system to adapt to the environment. However, functional assessment of ORs in related species remains largely untested. Here we investigated the functional properties of primate and rodent ORs t...
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ژورنال
عنوان ژورنال: Journal of Experimental Biology
سال: 2020
ISSN: 1477-9145,0022-0949
DOI: 10.1242/jeb.208215